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Casa 426 
Your Sanctuary in Centro Guadalajara

Welcome to Casa426, a cosmopolitan gaystay in the historic heart of Centro Guadalajara. Designed for the culturally curious traveler, our space blends warm, authentic hospitality in a rescued  neo-colonial era casona.  Here, you’re not just a tourist—you’re our houseguest, welcomed into the rhythm and energy of Mexico’s most creative and LGBTQ+ welcoming city

Your Urban GayStay

Casa426 is a great urban oasis for you and your chosen family. Unwind in a space that balances classic neo-colonial architecture with modern conveniences

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Our Rooms

 Large private air conditioned sleeping rooms have comfortable Queen or King-size beds and a private bathroom. Great retreat for a good night’s rest after a day (or night) of exploring and discovering

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 Our Common Space

 Spacious common areas have high ceilings,  a fully equipped kitchen, and a roof top terraza to relax, hang out, socialize, and feel at home

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Our Ammenities

100MB Wi-Fi, Comfortable beds,  desk and monitor, room refrigerator, coffee, purified water, room air conditioning, full house access, laundry machine, weekly cleaning

The Location: Centro Guadalajara

We are nestled in an authentic, vibrant, safe, walkable residential/ light commercial area of Centro Historico on a pedestrian street 800 meters north of the main Cathedral

- Prime location in the heart of the city
- Charming colonial and neo-colonial architecture
- Secure, walkable, vibrant, authentic neighborhood

< 1 minute walk: Shared bicycle and Metro station 

< 3 minute walk: Palacio Federal for Immigration

< 4 minute walk: Many cafes, food take-aways, taco stands, workout gyms, mercados,  pharmacies, Oxxo, farmacias, 

< 8-12 minute walk: Main Cathedral, temples, conventos, museums, theaters, and many other historical sites  

< 15 minute walk: Nuevas esquinas, more cool bars, restaurants, clubs, saunas 

< 7-10 minute Uber ride (100 pesos)  : Ave Chapultepec's nightlife bars, clubs, great parks, hiking, Central Vieja for short distance buses to Chapala, Tequila, 

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Why a Gaystay?

At Casa426, "gay-friendly" is our baseline—not our limit. We’re here to provide:

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Authentic Connection

With an American gay host who has made the transition to living in Guadalajara full time  over the last 5 years.   He understands the lay of the land and what you are likely to encounter.   Unlike your standard hotel or airbnb, he will directly answer your tough questions and help you find your people and what truly interests you.

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Beyond the Tourist Map

 We’ll connect you with the culture and help you make connections with other gay locals in your area of interest so that you can have unfiltered direct conversations.    We have a daily news feed of local events and can forward those that might be of interest

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Relevant Insights

 If you are considering moving to Mexico, there are 1001 things to consider.  Having recently been through the process, we can provide real life insights (including a gay perspective) and strategies to consider beyond the abundance of  generic, out-of-date, self-help articles and the abundance of conflicting information you find on FB groups.

The Vision of Casa 426

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More than a host—a creator of community.

Casa426 is the passion project of Brian Andrew, who rescued and reimagined a neglected century old casona in the heart of Centro. This isn't just his forever home.  It’s the foundation of a simple vision: to create a safe, inclusive, and welcoming space where anyone can be authentically themselves. Here, you're invited to explore, discover, and genuinely connect with the soul of Guadalajara.

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Building Gay Community Together

A core mission of Casa426 is to actively foster and support Guadalajara's vibrant LGBTQ+ ecosystem. Brian works to help local gay organizers and entrepreneurs create and grow their own ventures. 

  • In 2025, we provided the venue for a well-attended "Gaydalajara" Posada, helping an online community connect in person

  • We occasionally host one of the regular Sunday meetups for "Queers in Guadalajara," a growing FB group that brings together both locals and foreigners.

  • We’ve supported community entrepreneurs by hosting pop-up dinners and intimate live music events, turning Casa426 into a catalyst for local creativity.

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A Nudist Friendly Santuary

For those who embrace the clothing-optional lifestyle, Casa426 offers a unique, judgment-free sanctuary. Our private roof deck is a sun-drenched space where houseguests are free to bear all. When all houseguests agree, this clothing-free option can extend throughout the entire property.   We are an active member of the small but  growing Guadalajara nudist community and host several social nudist events here throughout the year, fostering a spirit of body positivity and liberation.

Calle Pedro Loza 426

Centro Historico

Guadalajara 44100, Jalisco MX

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© 2022-2026 Casa 426

All Rights Reserved

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